3-(Triethylsilyl)pyridine-2(1H)-thione CAS 116725-50-9
| CAS No. | 116725-50-9 |
| Molecular Formula | C11H19NSSi |
| Molecular Weight | 225.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Triethylsilyl)pyridine-2(1H)-thione is closely related to a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Triethylsilyl)pyridine-2(1H)-thione (CAS 116725-50-9) is a high-purity analytical reference standard with the molecular formula C11H19NSSi and a molecular weight of 225.43 g/mol.
3-(Triethylsilyl)pyridine-2(1H)-thione (C11H19NSSi) contains a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(Triethylsilyl)pyridine-2(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H19NSSi |
| Molecular Weight | 225.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Triethylsilyl Standards
- 2-(1-(Triethylsilyl)ethyl)pyridine (CAS 113948-60-0)
- Triethylsilyl 2-methylprop-2-ene-1-sulfinate (CAS 850418-19-8)
- Triethylsilyl allylcarbamate (CAS 61661-01-6)
- 1-Triethylsilyl-1-heptyne (CAS 1047660-72-9)
- 4-(Triethylsilyl)pyridin-3-ol (CAS 1001004-63-2)
- 3-(Triethylsilyl)quinoline (CAS 882049-74-3)
- 6-(Triethylsilyl)quinoline (CAS 67532-99-4)
- 5-(Triethylsilyl)pent-4-yn-1-ol (CAS 174064-02-9)
Recommended Standards
- 1-Bromo-2-chloro-1,1,2-trifluorobutane (CAS 1081534-24-8)
- 5-Bromo-4-chloro-1H-pyrazole-3-carboxylic acid (CAS 1934259-26-3)
- 4-Bromo-5-chlorofuran-2-carboxylic acid (CAS 31491-40-4)
- 5-Bromo-6-chloropyrimidine-2,4-diol (CAS 21428-23-9)
- Friedelin (CAS 559-74-0)
- 4-chloro-2,8-dimethyl-quinazoline (CAS 1429782-20-6)
- 1-{5-bromo-1H-thieno[3,2-c]pyrazol-1-yl}ethan-1-one (CAS 848357-82-4)
- 1-(4-chlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-60-2)
- 1-(N-Methyl-p-toluenesulfonamido)-cyclopentanecarboxylic acid (CAS 92697-49-9)
- N-(2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-(4-methylpiperidin-1-yl)acetamide (CAS 1704121-85-6)
- Perampanel Impurity 46 (CAS CATO-C4X-243046)
- 2-(1-Methyl-1H-pyrazol-4-yl)propan-2-amine (CAS 1215936-45-0)
- 5-Fluoro-2-(3-fluoro-5-(trifluoromethyl)pyridin-2-yl)-4-methyl-6-(methylthio)pyrimidine (CAS 1823183-51-2)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
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