6,8-Dichlorospiro[chroman-2,1'-cyclobutan]-4-one CAS 1169847-93-1
| CAS No. | 1169847-93-1 |
| Molecular Formula | C12H10Cl2O2 |
| Molecular Weight | 257.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.11 g/mol gives 6,8-Dichlorospiro[chroman-2,1'-cyclobutan]-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6,8-Dichlorospiro[chroman-2,1'-cyclobutan]-4-one (CAS 1169847-93-1), a certified reference material (molecular formula C12H10Cl2O2, MW 257.11 g/mol) for analytical method development and quality control.
6,8-Dichlorospiro[chroman-2,1'-cyclobutan]-4-one (C12H10Cl2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6,8-Dichlorospiro[chroman-2,1'-cyclobutan]-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2O2 |
| Molecular Weight | 257.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
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