4-(5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl)-1-(thiophen-2-ylmethyl)pyrrolidin-2-one CAS 1171583-48-4
| CAS No. | 1171583-48-4 |
| Molecular Formula | C17H14FN3O2S |
| Molecular Weight | 343.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl)-1-(thiophen-2-ylmethyl)pyrrolidin-2-one (CAS 1171583-48-4), molecular formula C17H14FN3O2S and molecular weight 343.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl)-1-(thiophen-2-ylmethyl)pyrrolidin-2-one (C17H14FN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14FN3O2S |
| Molecular Weight | 343.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 4-(5-(4-Fluorophenyl)-1,2,4-oxadiazol-3-yl)-1-(thiophen-2-ylmethyl)pyrrolidin-2-one (CAS 1171175-12-4)
- (5-(4-Fluorophenyl)-3-(prop-2-yn-1-ylthio)-1H-1,2,4-triazol-1-yl)(thiophen-2-yl)methanone (CAS 1024198-99-9)
- 1-(2-(4-Fluorophenyl)-2-morpholinoethyl)-3-phenylurea (CAS 941896-58-8)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-N-(4-methoxyphenyl)acetamide (CAS 303091-64-7)
- 2-(4-Fluorophenyl)-N-(2-(1-methyl-4-(thiophen-2-yl)-1H-imidazol-2-yl)ethyl)acetamide (CAS 1396764-96-7)
- 3-(2-Fluorophenyl)-N-(furan-2-ylmethyl)-N-(thiophen-3-ylmethyl)propanamide (CAS 1797074-14-6)
- 3-(2-Fluorophenyl)-N-(furan-3-ylmethyl)-N-(thiophen-2-ylmethyl)propanamide (CAS 1797214-33-5)
- (2Z)-2-[(2-Fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-yl thiophene-2-carboxylate (CAS 477871-49-1)
Recommended Standards
- 1-(2-((6-Morpholinopyrimidin-4-yl)oxy)ethyl)-3-phenylurea (CAS 1172501-91-5)
- 1-(2-Fluorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1170992-86-5)
- 5-(Morpholinosulfonyl)-N-(thiazol-2-yl)furan-2-carboxamide (CAS 1172811-31-2)
- ((4-Methoxyphenyl){2-oxo-2-[(2-pyridin-2-ylethyl)-amino]ethyl}amino)acetic acid 1142215-84-6 9471AC C18H21N3O4 (CAS 1142215-84-6)
- 1-(1,1-Dioxidothietan-3-yl)-3-ethylurea (CAS 1858860-67-9)
- 4-bromo-2-(4-fluorophenyl)-5-methoxypyridazin-3(2H)-one (CAS 10002-76-3)
- (5-Bromopyridin-3-yl)(phenyl)methanone (CAS 59105-50-9)
- (2-Chloro-4-fluorobenzyl)(3-chloro-5-fluorophenyl)sulfane (CAS 1443302-46-2)
- (1R*,4R*)-N1-Isopropylcyclohexane-1,4-diamine dihydrochloride (CAS 1286272-75-0)
- 4-(Heptyloxy)-N-[2-(phenethyloxy)benzyl]aniline (CAS 1040690-10-5)
- N-Trifluoroacetyl-3,4-(methylenedioxy)aniline (CAS 85575-56-0)
- 2-(Difluoromethyl)-4-hydroxy-6-methoxypyridine-3-sulfonyl chloride (CAS 1807129-01-6)
- (R)-3-chloro-1-(4-fluorophenyl)propan-1-ol (CAS 200004-39-3)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com