Ethyl 2-(4-oxo-8-(trifluoromethyl)quinolin-1(4H)-yl)acetate CAS 1171941-03-9
| CAS No. | 1171941-03-9 |
| Molecular Formula | C14H12F3NO3 |
| Molecular Weight | 299.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 299.25 g/mol gives Ethyl 2-(4-oxo-8-(trifluoromethyl)quinolin-1(4H)-yl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-(4-oxo-8-(trifluoromethyl)quinolin-1(4H)-yl)acetate (CAS 1171941-03-9), molecular formula C14H12F3NO3 and molecular weight 299.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 2-(4-oxo-8-(trifluoromethyl)quinolin-1(4H)-yl)acetate (C14H12F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 299.25 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12F3NO3 |
| Molecular Weight | 299.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ethyl 1-(3-aminophenyl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylate (CAS 1171543-02-4)
- Methyl 2-(2-methyl-4-oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetate (CAS 1208533-83-8)
- Ethyl 5-(Trifluoromethyl)-3-p-tolylisoxazole-4-carboxylate (CAS 1159978-84-3)
- 1-Isopropyl-4-oxo-7-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 1210193-69-3)
- 3-Acetamido-6-acetyl-2-nitrophenyl 4-(benzyl(methyl)amino)-3,5-difluorobenzoate (CAS 1548406-01-4)
- (R)-(5-Bromo-6-fluoro-1,2,3,4-tetrahydroisoquinolin-3-yl)methanol (CAS 2766834-67-5)
- n-Isopropyl-2,3-dimethylcyclohexan-1-amine (CAS 1053161-17-3)
- 4-(Hydrazinecarbonyl)-N-(pyridin-4-yl)-1H-imidazole-5-carboxamide (CAS 627470-11-5)
- 3-Chloro-2,4-pentanedione (CAS 1694-29-7)
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- Methyl 3-acetyl-5-formylbenzoate (CAS 1393581-87-7)
- Amyrin Impurity 4 (CAS 152487-61-1)
- 3-(Chlorosulfonyl)-4-isopropylbenzoic acid (CAS 59815-29-1)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
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