Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate CAS 1172010-69-3
| CAS No. | 1172010-69-3 |
| Molecular Formula | C18H19F2N5O2 |
| Molecular Weight | 375.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1172010-69-3), molecular formula C18H19F2N5O2 and molecular weight 375.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (C18H19F2N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19F2N5O2 |
| Molecular Weight | 375.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Ethyl Standards
- 2-[3-cyclopropyl-4-(difluoromethyl)-6-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1006478-14-3)
- 1-Cyclopropyl-8-ethoxy-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 112811-83-3)
- 2-[3-cyclopropyl-6-(4-methylphenyl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937606-10-5)
- 1-(5-Cyclopropyl-2-phenyloxazole-4-carbonyl)-N-methylpyrrolidine-3-sulfonamide (CAS 1808777-05-0)
- cyclopropyl 2-(3,5-dimethylphenyl)ethyl ketone (CAS 898777-44-1)
- N-(2-(5-Cyclopropyl-3-(pyridin-4-yl)-1H-pyrazol-1-yl)ethyl)thiophene-2-sulfonamide (CAS 1797616-44-4)
- 3-Cyclopropyl-1-((4-iodophenyl)sulfonyl)-1H-pyrazole (CAS 956783-71-4)
- 6-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl Acetate (CAS 1544531-48-7)
Recommended Standards
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