1-[4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl]piperidin-4-amine CAS 1172829-91-2
| CAS No. | 1172829-91-2 |
| Molecular Formula | C16H22F2N6 |
| Molecular Weight | 336.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 1-[4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl]piperidin-4-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 336.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-[4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl]piperidin-4-amine (CAS 1172829-91-2), a certified reference material (molecular formula C16H22F2N6, MW 336.38 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-[4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl]piperidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H22F2N6 |
| Molecular Weight | 336.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related difluoromethyl Standards
- 1-[4-(difluoromethyl)-6-(1-ethyl-3-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl]piperidin-4-amine (CAS 1172393-77-9)
- 3-[7-(difluoromethyl)-5-(1,3-dimethyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1171048-28-4)
- 3-[7-(difluoromethyl)-5-(1,5-dimethyl-1h-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1172726-60-1)
- 3-(7-(Difluoromethyl)-5-(1-ethyl-1h-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid (CAS 1174874-40-8)
- 3-(Difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxylic acid (CAS 1369490-06-1)
- 4-(Difluoromethyl)-6-iodo-3-methyl-2-(trifluoromethyl)pyridine (CAS 1804867-49-9)
- 4-(Difluoromethyl)-5-iodo-2-methyl-3-(trifluoromethyl)pyridine (CAS 1805536-13-3)
- 2-(Difluoromethyl)-3-iodo-4-methyl-5-(trifluoromethyl)pyridine (CAS 1806950-63-9)
Recommended Standards
- (3R,4R)-3-tert-Butoxycarbonylamino-4-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester (CAS 1203566-76-0)
- 2-Methoxy-6-(naphthalen-2-ylmethoxymethyl)-benzoic acid methyl ester (CAS 1171923-82-2)
- N-(2-(2,4-Dioxothiazolidin-3-yl)cyclohexyl)-2-fluorobenzamide (CAS 1207038-95-6)
- 2-Methoxy-6-(naphthalen-1-ylmethoxymethyl)-benzoic acid methyl ester (CAS 1171923-66-2)
- 4-(Chloromethyl)-2-(difluoromethyl)-5-hydroxynicotinonitrile (CAS 1806985-80-7)
- (1-Methylpentyl)cyclopropane (CAS 6976-28-9)
- Methyl 1,4-dichlorophthalazine-6-carboxylate (CAS 1416713-80-8)
- ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate (CAS CATO-C3D-262458)
- 2-((1-Amino-2-methyl-1-oxopropan-2-yl)amino)-2-oxoacetic acid (CAS 855842-90-9)
- 2-Chloro-5-(4-(trifluoromethyl)phenyl)oxazole (CAS 1238893-96-3)
- 1H-Imidazole-2-carboxamide, 4,5-dihydro-N-(2,3,5,6-tetrabromo-4-methoxyphenyl)- (CAS 905105-89-7)
- (1R,2S,4S)-2-Chloro-1-isopropyl-4-methylcyclohexane (CAS 104012-59-1)
- 8-Bromoquinolin-4(1H)-one (CAS 949507-29-3)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com