5-Amino-4-chloro-2-methylbenzonitrile CAS 1173434-90-6
| CAS No. | 1173434-90-6 |
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-4-chloro-2-methylbenzonitrile.
5-Amino-4-chloro-2-methylbenzonitrile (CAS 1173434-90-6), molecular formula C8H7ClN2 and molecular weight 166.61 g/mol, is a CATO reference standard with documented purity and traceability.
5-Amino-4-chloro-2-methylbenzonitrile (C8H7ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Amino-4-chloro-2-methylbenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 6-Amino-3-chloro-2-methylbenzonitrile (CAS 110127-06-5)
- 2-(3-Amino-5-chlorophenyl)acetonitrile (CAS 1261470-81-8)
- 2-(3-Amino-4-chlorophenyl)acetonitrile (CAS 1261580-99-7)
- 4-Amino-3-chloro-5-methylbenzonitrile (CAS 158296-69-6)
- 7-Amino-3-chloro-1H-indole (CAS 165669-13-6)
- 2-(4-Amino-2-chlorophenyl)acetonitrile (CAS 180150-18-9)
- 2-(2-amino-5-chlorophenyl)acetonitrile (CAS 197659-75-9)
- 2-(2-Amino-3-chlorophenyl)acetonitrile (CAS 95339-68-7)
Recommended Standards
- 6-Chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1150618-33-9)
- 1-Chloro-7-methylpyrrolo[1,2-a]pyrazine (CAS 118355-96-7)
- 6-Chloro-2-ethylnicotinonitrile (CAS 1150103-22-2)
- 6-Chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1190311-77-3)
- 4-Amino-5-(methylthio)-1H-pyrazole-3-carboxamide (CAS 28668-18-0)
- 3-Methyl-4-(4-methyl-2-nitrophenoxy)-[1,2]oxazolo[5,4-d]pyrimidine (CAS 672925-27-8)
- N-((5-(aminomethyl)furan-2-yl)methyl)-N-propylpropan-1-amine (CAS 1170183-16-0)
- 4-Ethyl-3-(2-iodophenyl)-1h-pyrazol-5-amine (CAS 1187561-46-1)
- 1-(Thiophen-2-ylmethyl)-1h-1,2,3,4-tetrazole-5-thiol (CAS 872108-04-8)
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- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
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