2-Acetylamino-5-thiazolecarboxylic acid methyl ester CAS 1174534-36-1
| CAS No. | 1174534-36-1 |
| Molecular Formula | C7H8N2O3S |
| Molecular Weight | 200.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Acetylamino-5-thiazolecarboxylic acid methyl ester (CAS 1174534-36-1), a certified reference material (molecular formula C7H8N2O3S, MW 200.22 g/mol) for analytical method development and quality control.
The molecular framework of 2-Acetylamino-5-thiazolecarboxylic acid methyl ester (C7H8N2O3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O3S |
| Molecular Weight | 200.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Acetylamino Standards
- (2-Acetylamino-thiazol-4-yl)-acetic acid (CAS 202408-30-8)
- 2-Acetylamino-4-methylthiazole-5-carboxylic acid (CAS 63788-62-5)
- 3-Acetylamino-5-nitrobenzoicacid (CAS 5464-58-4)
- (Acetylamino)(2-thienyl)acetic acid (CAS 68802-32-4)
- N-[2-(acetylamino)-1,3-thiazol-5-yl]acetamide (CAS 72130-94-0)
- 3-(Acetylamino)benzoyl chloride (CAS 90531-74-1)
- 2-(acetylamino)-4-amino-2,4,6-trideoxy-alpha-D-Galactopyranose (CAS 1644434-29-6)
- 2-(Acetylamino)-3-phenyl-2-propenoic acid (CAS 5469-45-4)
Recommended Standards
- [2-(Methylthio)-6-oxo-1,6-dihydropyrimidin-4-yl]acetic acid (CAS 1170224-11-9)
- 4-(Cyanomethyl)-1-methyl-1H-pyrazole-5-sulfonamide (CAS 117519-66-1)
- 2-(Acetamidomethyl)thiazole-4-carboxylic acid (CAS 1147111-43-0)
- Methyl 2-(3-carbamothioyl-1h-1,2,4-triazol-1-yl)acetate (CAS 1193387-92-6)
- n-(2-Bromobenzyl)pyridin-3-amine (CAS 1019538-65-8)
- Acitretin (CAS 55079-83-9)
- 1-[4-(1,1-Dioxido-1,2-benzisothiazol-3-yl)-piperazin-1-yl]propan-2-ol (CAS 346448-88-2)
- 3-Bromo-5-methoxy-2-methylpyridine (CAS 1256823-49-0)
- (1-(3-Fluoro-4-methoxybenzyl)piperidin-4-yl)methanol (CAS 1252332-11-8)
- Methyl 2-amino-2,3-dihydro-1H-indene-5-carboxylate (CAS 915764-21-5)
- 1-Bromo-3-octylbenzene (CAS 663949-34-6)
- (S)-2-amino-4-phenylbutan-1-ol hydrochloride (CAS 150935-38-9)
- 5-(Neopentyloxy)pyridazin-3(2H)-one (CAS 1346697-79-7)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com