Rasagiline Impurity 13 HCl CAS 1175018-75-3
| CAS No. | 1175018-75-3 |
| Molecular Formula | C12H14ClN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Rasagiline Impurity 13 HCl (CAS 1175018-75-3, C12H14ClNHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Rasagiline Impurity 13 HCl is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 244.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Rasagiline Impurity 13 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14ClN HCl |
| Molecular Weight | 244.16 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Rasagiline Standards
- Rasagiline Impurity 16 (CAS 100516-95-8)
- Rasagiline Impurity 75 HCl (CAS 1016719-48-4 (free base))
- Rasagiline Impurity 42 (CAS 1028-21-3)
- Rasagiline Impurity 16 HCl (CAS 10409-00-4)
- Rasagiline Impurity 43 (CAS 108701-34-4)
- Rasagiline Impurity 52 (CAS 113535-01-6)
- Rasagiline Impurity 20 (CAS 1166392-42-2)
- Rasagiline Impurity 73 (CAS 1175018-73-1(free base))
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