5-Bromoisoquinolin-3(2H)-one CAS 1175271-86-9
| CAS No. | 1175271-86-9 |
| Molecular Formula | C9H6BrNO |
| Molecular Weight | 224.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromoisoquinolin-3(2H)-one.
5-Bromoisoquinolin-3(2H)-one (CAS 1175271-86-9), molecular formula C9H6BrNO and molecular weight 224.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromoisoquinolin-3(2H)-one (C9H6BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6BrNO |
| Molecular Weight | 224.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromoisoquinolin Standards
- 6-Bromoisoquinolin-4-ol (CAS 1015070-56-0)
- 6-Bromoisoquinolin-3(2H)-one (CAS 1031927-91-9)
- 8-Bromoisoquinolin-5-ol (CAS 1057962-05-6)
- 6-bromoisoquinolin-7-ol (CAS 1148110-19-3)
- 8-Bromoisoquinolin-6-ol (CAS 1220694-88-1)
- 7-Bromoisoquinolin-4-ol (CAS 1402886-92-3)
- 4-Bromoisoquinolin-7-ol (CAS 1783631-45-7)
- 4-Bromoisoquinolin-8-ol (CAS 1784957-23-8)
Recommended Standards
- 8-bromoquinolin-5-ol (CAS 116836-28-3)
- 5-Bromo-8-hydroxyquinoline (CAS 1198-14-7)
- 2-Bromoquinolin-7-ol (CAS 1165801-18-2)
- 3-Bromoquinolin-7-ol (CAS 1160949-99-4)
- Neopentyl-tBu2P Pd G2 (CAS 2230788-59-5)
- (R)-3-(Piperidin-2-yl)pyridine hydrochloride (CAS 1055196-29-6)
- 2-(7-Amino-3,4-dihydroisoquinolin-2(1H)-yl)ethanol (CAS 751461-70-8)
- 4-(4-Methylpiperazinomethyl)-4-trifluoromethylbenzophenone (CAS 898783-95-4)
- (2-(tert-Butoxycarbonyl)-5-methoxyphenyl)boronicacid (CAS 1309981-67-6)
- N-(5,6,7,8-tetrahydroisoquinolin-1-yl)acetamide (CAS 477532-04-0)
- Eldecalcitol Impurity 56 (CAS 66774-82-1)
- Apremilast impurity 18 (CAS 1384439-79-5)
- 3-Chloro-3-ethylhexane (CAS 116530-76-8)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com