(Z)-Ethyl 3-(cyclopropylamino)-2-(2,4-dichloro-3-cyano-5-fluorobenzoyl)acrylate CAS 117528-63-9
| CAS No. | 117528-63-9 |
| Molecular Formula | C16H13Cl2FN2O3 |
| Molecular Weight | 371.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(Z)-Ethyl 3-(cyclopropylamino)-2-(2,4-dichloro-3-cyano-5-fluorobenzoyl)acrylate (CAS 117528-63-9), molecular formula C16H13Cl2FN2O3 and molecular weight 371.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (Z)-Ethyl 3-(cyclopropylamino)-2-(2,4-dichloro-3-cyano-5-fluorobenzoyl)acrylate (C16H13Cl2FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 371.19 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (Z)-Ethyl 3-(cyclopropylamino)-2-(2,4-dichloro-3-cyano-5-fluorobenzoyl)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl2FN2O3 |
| Molecular Weight | 371.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tributyl(cyclohex-1-en-1-yl)stannane (CAS 100073-20-9)
- 4,6-Dichloro-2-(2,4-dimethoxybenzyl)-7-fluoro-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one (CAS 1312691-38-5)
- Methyl 2-(3-bromo-2-methylphenyl)-7-cyanobenzo[d]oxazole-5-carboxylate (CAS 2459479-71-9)
- n,n-Bis(2-hydroxyethyl)-4-iodobenzenesulfonamide (CAS 161431-66-9)
- 2-(2-hydroxyethyl)cyclobutanone (CAS 97452-31-8)
- (4-(((N,N-dimethylsulfamoyl)amino)methyl)phenyl)boronic acid (CAS 2246894-62-0)
- 1-Methylindoline-7-carboxylic acid (CAS 289725-22-0)
- 6-bromo-4-fluoro-3H-1,3-benzoxazol-2-one (CAS 1780002-65-4)
- tert-Butyl (4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)phenyl)carbamate (CAS 2007909-81-9)
- 5-Methyl-2-(methylamino)benzene-1-thiol (CAS 79226-39-4)
- 2-Methyl-8-((trimethylsilyl)oxy)quinoline (CAS 54397-25-0)
- (3-(3-Methyl-1,2,4-oxadiazol-5-yl)azetidin-1-yl)(1-(thiophen-2-yl)cyclopentyl)methanone (CAS 1286725-95-8)
- 4-Bromo-5-hexylthiophene-2-carboxylic acid (CAS 478166-01-7)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com