2-chloro-N-methyl-5-propanoylbenzene-1-sulfonamide CAS 1175862-48-2
| CAS No. | 1175862-48-2 |
| Molecular Formula | C10H12ClNO3S |
| Molecular Weight | 261.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-chloro-N-methyl-5-propanoylbenzene-1-sulfonamide (CAS 1175862-48-2), molecular formula C10H12ClNO3S and molecular weight 261.73 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-chloro-N-methyl-5-propanoylbenzene-1-sulfonamide (C10H12ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO3S |
| Molecular Weight | 261.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chloro Standards
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Recommended Standards
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- 4-(3-CHlorobenzenesulfonyl)morpholine (CAS 1089591-41-2)
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- (R)-2-(2-(1,3-Dioxan-2-yl)ethyl)-1-methylpyrrolidine (2R,3R)-2,3-bis(benzyloxy)succinate (CAS 868618-81-9)
- Methyl 2-deoxy-3-5-di-O-toluoyl-D-ribofuranoside (CAS 4330-34-1)
- 4-bromo-1-(3-methoxypropanesulfonyl)piperidine (CAS 1502579-29-4)
- Methyl 1-Methyl-5-[4-(trifluoromethyl)phenyl]pyrrole-2-carboxylate (CAS 1895780-61-6)
- 3-(Difluoromethyl)-5-fluoro-6-oxo-1,6-dihydropyridine-2-carbonitrile (CAS 1804484-49-8)
- 2-Amino-2-(4-(tert-butyl)phenyl)propan-1-ol (CAS 187585-57-5)
- 1-(5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1H-imidazole-4-carboxylic acid (CAS 1281990-08-6)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
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