5-(Chloromethyl)-6-methylbenzo[d][1,3]dioxole CAS 117661-72-0
| CAS No. | 117661-72-0 |
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(Chloromethyl)-6-methylbenzo[d][1,3]dioxole (CAS 117661-72-0), molecular formula C9H9ClO2 and molecular weight 184.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-(Chloromethyl)-6-methylbenzo[d][1,3]dioxole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-(Chloromethyl)-6-methylbenzo[d][1,3]dioxole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)phenyl acetate (CAS 15068-08-3)
- 2-(Chloromethyl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one (CAS 1518133-04-4)
- 3-(Chloromethyl)-2-hydroxy-5-methylbenzaldehyde (CAS 192819-68-4)
- (3-Chloromethyl-phenyl)-acetic acid (CAS 857165-45-8)
- 1-(5-(Chloromethyl)-2-hydroxyphenyl)ethanone (CAS 30787-43-0)
- 2-(Chloromethyl)phenyl isocyanate (CAS 52986-66-0)
- 2-(CHLOROMETHYL)PHENYLACETIC ACID (CAS 95335-46-9)
- 2-Chloromethyl-2,3-dihydro-benzo[1,4]dioxine (CAS 2164-33-2)
Recommended Standards
- 8-chloro-3,4-dihydro-2H-1-benzopyran-4-ol (CAS 1176104-70-3)
- 2-Chloro-5-(2-hydroxyethyl)benzaldehyde (CAS 1179337-94-0)
- 5-Cyclopropyl-1-methyl-1H-pyrazole-3-carbonyl chloride (CAS 1174311-14-8)
- 2-Chloro-6-(dimethylamino)nicotinaldehyde (CAS 1186405-06-0)
- s-Triazine-1,3,5-triethanol (CAS 4719-04-4)
- Gal[246Bn,3All]-β-SPh (CAS 1017587-57-3)
- (E)-Dodeca-9,11-dien-1-yl acetate (CAS 50767-78-7)
- (S)-Benzyl 4-(2-amino-3-methylbutanoyl)piperazine-1-carboxylate (CAS 149991-64-0)
- 4-(4-Aminobutyl)-5-(pyridin-4-yl)-1H-pyrazol-3(2H)-one (CAS 878208-90-3)
- 2-(Ethylamino)-2-(p-tolyl)acetonitrile hydrochloride (CAS 1440535-75-0)
- (2,4-Dimethyl-5-nitrophenyl)boronic acid (CAS 319474-09-4)
- 2'-Formyl-[1,1'-biphenyl]-2-carboxylic acid (CAS 6720-26-9)
- 1-(3-Nitrophenyl)azetidin-3-ol (CAS 1301138-57-7)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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