3,4-Dichloro-N-(pyrrolidin-2-ylmethyl)aniline dioxalate CAS 1177282-35-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1177282-35-7
Molecular FormulaC11H14Cl2N2
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,4-Dichloro-N-(pyrrolidin-2-ylmethyl)aniline dioxalate CAS 1177282-35-7 chemical structure

Description

The occurrence of 3,4-Dichloro-N-(pyrrolidin-2-ylmethyl)aniline dioxalate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3,4-Dichloro-N-(pyrrolidin-2-ylmethyl)aniline dioxalate (CAS 1177282-35-7), molecular formula C11H14Cl2N2C2H2O4 and molecular weight 335.18 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3,4-Dichloro-N-(pyrrolidin-2-ylmethyl)aniline dioxalate (C11H14Cl2N2C2H2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H14Cl2N2 2*C2H2O4
Molecular Weight335.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms2

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