2-(Chloromethyl)-4-phenylthiazole hydrochloride CAS 1177287-80-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1177287-80-7
Molecular FormulaC10H8ClNS
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Chloromethyl)-4-phenylthiazole hydrochloride CAS 1177287-80-7 chemical structure

Description

The occurrence of 2-(Chloromethyl)-4-phenylthiazole hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Chloromethyl)-4-phenylthiazole hydrochloride (CAS 1177287-80-7), molecular formula C10H8ClNSHCl and molecular weight 246.15 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-(Chloromethyl)-4-phenylthiazole hydrochloride (C10H8ClNSHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 246.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Chloromethyl)-4-phenylthiazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8ClNS HCl
Molecular Weight246.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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