1,8-Naphthyridine-3,6-diamine CAS 1177337-61-9
| CAS No. | 1177337-61-9 |
| Molecular Formula | C8H8N4 |
| Molecular Weight | 160.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1,8-Naphthyridine-3,6-diamine (CAS 1177337-61-9), a certified reference material (molecular formula C8H8N4, MW 160.18 g/mol) for analytical method development and quality control.
The molecular framework of 1,8-Naphthyridine-3,6-diamine (C8H8N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8N4 |
| Molecular Weight | 160.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Naphthyridine Standards
- 1,8-Naphthyridine-2,7-diamine (CAS 145325-89-9)
- 1,5-Naphthyridine-2,7-diamine (CAS 1509360-66-0)
- 1,6-Naphthyridine-3,8-diamine (CAS 1864060-88-7)
- 1,5-Naphthyridine-2,3-diamine (CAS 50786-31-7)
- 1,5-Naphthyridine-2,6-diamine (CAS 42309-17-1)
- 1,8-Naphthyridine-3,4-diamine (CAS 72235-44-0)
- 2,6-Naphthyridine-1,5-diamine (CAS 81044-13-5)
- 1,6-Naphthyridine-5,7(6H,8H)-dione (CAS 1345461-33-7)
Recommended Standards
- 2-(2H-1,2,3-Triazol-2-yl)aniline (CAS 1173462-33-3)
- 7-Methylpyrido[2,3-d]pyrimidin-4-amine (CAS 120266-91-3)
- 5-Pyrazol-1-yl-pyridin-2-ylamine (CAS 1152839-05-8)
- 1-(Pyridin-3-yl)-1H-imidazol-2-amine (CAS 1211541-66-0)
- N-(5-fluoro-2-methylphenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 303091-61-4)
- 8-Chloro-2-(2,4-dichlorophenyl)quinoline-4-carboxylic acid (CAS 863180-69-2)
- 1-Chloro-4-(2-methylpropoxy)-2-(trifluoromethyl)benzene (CAS 1881290-46-5)
- Tetrahydro-2H-thiopyran-2-carbonyl chloride (CAS 147164-54-3)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with ethyl 2-propenoate and 2-oxiranylmethyl 2-methyl-2-propenoate (CAS 25153-49-5)
- 1-(2-methoxyphenyl)hexahydropyrimidine-2,4-dione (CAS 23947-33-3)
- 2-((1H-Indol-3-yl)methyl)benzoic acid (CAS 1221-99-4)
- (5Z)-2-Phenyl-5-(phenylmethylene)-4(5H)-thiazolone (CAS 1924637-65-9)
- Upadacitinib Impurity 46 (CAS 875781-43-4)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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