1-(2-FLuorophenyl)-2,3,4,9-tetrahydro-1h-b-carboline, HCl CAS 1177348-44-5
| CAS No. | 1177348-44-5 |
| Molecular Formula | C17H15FN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(2-FLuorophenyl)-2,3,4,9-tetrahydro-1h-b-carboline, HCl (CAS 1177348-44-5) is a high-purity analytical reference standard with the molecular formula C17H15FN2HCl and a molecular weight of 302.78 g/mol.
The molecular framework of 1-(2-FLuorophenyl)-2,3,4,9-tetrahydro-1h-b-carboline, HCl (C17H15FN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15FN2 HCl |
| Molecular Weight | 302.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related FLuorophenyl Standards
- 3-[(3-fluorophenyl)methyl]pyrrolidine (CAS 1000198-80-0)
- 3-(3-Fluorophenyl)-3-oxopropanoic acid (CAS 1000530-96-0)
- Ethyl 1-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000573-68-1)
- 1000574-26-4 2-(4-Fluorophenyl)-6-methylthio-4H-thiopyran-4-one MFCD09877819 (CAS 1000574-26-4)
- Ethyl 1-(2-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000575-18-7)
- 100074-04-2 5-(4-Fluorophenyl)-1-pentene MFCD11553774 (CAS 100074-04-2)
- 3-(2-Fluorophenyl)-4-hydroxyfuran-2(5H)-one (CAS 100074-44-0)
- N-[2-(4-fluorophenyl)ethyl]-1H-imidazole-1-carboxamide (CAS 1000931-75-8)
Recommended Standards
- 4-Methyl-N-(pentan-3-yl)pyridin-2-amine (CAS 1249259-04-8)
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- 2-(Ethoxycarbonyl)-1-cyclohexene-1-boronic Acid Pinacol Ester (CAS 497959-39-4)
- (2R,3S,4R,5S,6S)-2-(2-azidoethoxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol (CAS 153252-86-9)
- (4-(Cyclopropylcarbamoyl)-3-fluorophenyl)boronic acid (CAS 874289-20-0)
- 4-(3-Bromo-4-methylbenzyl)morpholine (CAS 1414870-70-4)
- Ethyl 3-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3-iminopropanoate (CAS 337919-63-8)
- 2,7-Dinitrophenanthrene-9,10-dione (CAS 604-94-4)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
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