2-(2-Methoxy-3-methylphenyl)pyrrolidine hydrochloride CAS 1177352-20-3
| CAS No. | 1177352-20-3 |
| Molecular Formula | C12H17NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Methoxy-3-methylphenyl)pyrrolidine hydrochloride.
CATO supplies 2-(2-Methoxy-3-methylphenyl)pyrrolidine hydrochloride (CAS 1177352-20-3), a certified reference material (molecular formula C12H17NOHCl, MW 227.73 g/mol) for analytical method development and quality control.
2-(2-Methoxy-3-methylphenyl)pyrrolidine hydrochloride (C12H17NOHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-Methoxy-3-methylphenyl)pyrrolidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17NO HCl |
| Molecular Weight | 227.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 1-(2-Methoxy-6-(methylsulfonyl)phenyl)piperazine (CAS 1000018-42-7)
- 6-methoxy-1-methyl-1H-1,3-benzodiazol-7-amine (CAS 1000202-26-5)
- 2-Methoxy-3-(trifluoromethyl)benzaldehyde (CAS 1000339-54-7)
- 1-Methoxy-3-methyl-5-(trifluoromethoxy)benzene (CAS 1000339-56-9)
- 5-Methoxy-7-methyl-1H-indazole-3-carbaldehyde (CAS 1000340-55-5)
- 5-Methoxy-7-methyl-1H-indazole-3-carboxylic acid (CAS 1000340-57-7)
- 5-Methoxy-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-90-8)
- 6-Methoxy-4-nitro-1H-indazole (CAS 1000341-08-1)
Recommended Standards
- 7-fluoro-[1,2,4]triazolo[4,3-a]pyridine-3-carbaldehyde (CAS 1785486-52-3)
- 1-Methyl-2-((trimethylsilyl)amino)-1H-imidazol-4(5H)-one (CAS 96681-94-6)
- 1-(1-Cyclopropylethyl)-4-methyl-1h-pyrazolo[3,4-b]pyridin-6-yl 4-methylbenzene-1-sulfonate (CAS 929975-64-4)
- 5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carbonitrile (CAS 863868-52-4)
- (4-Hydroxyphenyl)dimethylsulfonium hexafluorophosphate(V) (CAS 59626-68-5)
- (S)-N-(2,4-Dichlorobenzyl)-N-propylpyrrolidin-3-amine (CAS 820981-46-2)
- 7-Fluoro-1H-indole-3-carbonitrile (CAS 1043601-55-3)
- N-(2-(Cyclopropyl(2-hydroxyethyl)amino)cyclohexyl)acetamide (CAS 1353957-96-6)
- 2,2,4-Trimethyl-1,2-dihydroquinolin-6-yl 3-fluorobenzoate (CAS 714278-29-2)
- Lixisenatide (CAS 320367-13-3（free base）)
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