4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine dihydrochloride CAS 1177618-54-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine dihydrochloride.

4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine dihydrochloride (CAS 1177618-54-0) is a high-purity analytical reference standard with the molecular formula C14H9Cl2N3SHCl and a molecular weight of 358.67 g/mol.

4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine dihydrochloride (C14H9Cl2N3SHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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