4'-(Tert-butyl)-7-hydroxyspiro[chromane-2,1'-cyclohexan]-4-one CAS 1177835-40-3
| CAS No. | 1177835-40-3 |
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4'-(Tert-butyl)-7-hydroxyspiro[chromane-2,1'-cyclohexan]-4-one (CAS 1177835-40-3), molecular formula C18H24O3 and molecular weight 288.38 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4'-(Tert-butyl)-7-hydroxyspiro[chromane-2,1'-cyclohexan]-4-one (C18H24O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 288.38 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Recommended Standards
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(phenylmethyl)-, 1,1-dimethylethyl ester (CAS 1167424-93-2)
- N-(2,2-Dimethoxyethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine Hydrochloride (CAS 121593-91-7)
- Benzyl 1,8-diazaspiro[4.6]undecane-8-carboxylate (CAS 1160246-79-6)
- tert-Butyl 3-benzyl-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate (CAS 122828-36-8)
- 4-Hydroxy-2-methyl-7-trifluoromethylquinoline (CAS 15912-66-0)
- Ethyl 2-((4-chloro-3-(trifluoromethyl)phenyl)amino)thiazole-4-carboxylate (CAS 860612-32-4)
- methyl rac-(3R,4S)-2-oxo-4-phenylpyrrolidine-3-carboxylate (CAS 1627955-76-3)
- 1-(Furo[3,2-b]pyridin-6-yl)ethanone (CAS 1203499-00-6)
- Piribedil Impurity N2 (CAS 263-29-6)
- N-(2-((3-cyano-4,6-dimethylpyridin-2-yl)thio)phenyl)-4-fluorobenzamide (CAS 478045-71-5)
- (3-Fluoro-4-iodopyridin-2-yl)methanamine (CAS 1805589-86-9)
- 3-((4-Methoxybenzyl)oxy)benzaldehyde (CAS 108781-14-2)
- 1-Cyclobutylcyclopropanecarboxylic acid (CAS 1601751-12-5)
- [Nva12]-Tirzepatide (CAS CATO-C4X-324042)
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