4-Chloro-3-(methanesulfonylmethyl)aniline CAS 1178024-93-5
| CAS No. | 1178024-93-5 |
| Molecular Formula | C8H10ClNO2S |
| Molecular Weight | 219.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-3-(methanesulfonylmethyl)aniline (CAS 1178024-93-5) is a high-purity analytical reference standard with the molecular formula C8H10ClNO2S and a molecular weight of 219.69 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-3-(methanesulfonylmethyl)aniline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-3-(methanesulfonylmethyl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO2S |
| Molecular Weight | 219.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 4-Chloro-2-((methylsulfonyl)methyl)aniline (CAS 1101063-19-7)
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- 2-chloro-5-(methanesulfonylmethyl)aniline (CAS 1184114-42-8)
Recommended Standards
- N-((5-chlorothiophen-2-yl)methyl)-N-methylglycine (CAS 1155505-27-3)
- 3-Chlorobenzo[4,5]thieno[2,3-b]pyridine (CAS 118726-30-0)
- N-[4-(chloromethyl)phenyl]methanesulfonamide (CAS 1152540-47-0)
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- 3-{5-methyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridine (CAS 954219-31-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com