5,6-Dehydro-N-methyl Desloratadine CAS 117811-18-4
| CAS No. | 117811-18-4 |
| Molecular Formula | C20H19ClN2 |
| Molecular Weight | 322.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5,6-Dehydro-N-methyl Desloratadine (CAS 117811-18-4), a pharmacopoeial impurity reference standard (molecular formula C20H19ClN2, MW 322.83 g/mol) used for the identification and quantification of trace impurities in APIs.
5,6-Dehydro-N-methyl Desloratadine (C20H19ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19ClN2 |
| Molecular Weight | 322.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dehydro Standards
- Dehydro Monocrotaline (CAS 23291-96-5)
- 2-Dehydro-3-methoxy Tibolone (1.0mg/ml in Acetonitrile) (CAS 15506-05-5)
- 2-Dehydro-3-methoxy 7β-Tibolone (1.0mg/ml in Acetonitrile) (CAS 32297-44-2)
- 3-Dehydro Retinol Acetate (CAS 20008-04-2)
- 3-Dehydro Retinol Acetate-d3 (CAS 1795137-64-2)
- 11-Dehydro-Progesterone (CAS 2625-60-7)
- Dehydro Warfarin-d5 (CAS 1346606-43-6)
- Dehydro desloratadine (CAS 117811-20-8)
Recommended Standards
- Tert-butyl 5-chlorospiro[indoline-3,4'-piperidine]-1-carboxylate (CAS 1160247-22-2)
- 1-(2-(4-(4-Chlorophenyl)piperazin-1-yl)ethyl)-3-cyclopropylurea (CAS 1207054-99-6)
- tert-Butyl 4-chlorospiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 1129432-44-5)
- 3-(4-Chlorophenyl)-5,6-dimethyl-2-sulfanylthieno[2,3-d]pyrimidin-4(3h)-one (CAS 126105-97-3)
- Dutasteride EP Impurity I (CAS 3088800-46-5)
- Enarodustat Impurity 3 (CAS CATO-C4X-32283)
- Nebivolol Impurity 79 (CAS CATO-C4X-196879)
- 2-Cyclopropoxy-1-ethyl-3-(trifluoromethyl)benzene (CAS 1243462-47-6)
- 2-(3-(2-Fluorophenyl)-2-oxoimidazolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)acetamide (CAS 1251688-18-2)
- N-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methanesulfonamide (CAS 1201643-71-1)
- (R)-3-((tert-Butoxycarbonyl)amino)-3-cyclopentylpropanoic acid (CAS 1260604-42-9)
- 7-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1567214-36-1)
- Eravacycline impurity 34 (CAS CATO-C4X-293834)
- Neuropeptide Y (2-36) (human, rat) trifluoroacetate salt (CAS 123139-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com