2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid CAS 1178280-85-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1178280-85-7
Molecular FormulaC11H9FN2O2
Molecular Weight220.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid CAS 1178280-85-7 chemical structure

Description

The occurrence of 2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid (CAS 1178280-85-7), molecular formula C11H9FN2O2 and molecular weight 220.20 g/mol, is a CATO reference standard with documented purity and traceability.

2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid (C11H9FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H9FN2O2
Molecular Weight220.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms2

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