1-(2,2-Difluoroethyl)-N-methylpiperidin-4-amine CAS 1178346-64-9
| CAS No. | 1178346-64-9 |
| Molecular Formula | C8H16F2N2 |
| Molecular Weight | 178.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2,2-Difluoroethyl)-N-methylpiperidin-4-amine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(2,2-Difluoroethyl)-N-methylpiperidin-4-amine (CAS 1178346-64-9), a certified reference material (molecular formula C8H16F2N2, MW 178.22 g/mol) for analytical method development and quality control.
Structurally, 1-(2,2-Difluoroethyl)-N-methylpiperidin-4-amine (C8H16F2N2) contains fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 178.22 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)-N-methylpiperidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H16F2N2 |
| Molecular Weight | 178.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoroethyl Standards
- (1-(2,2-Difluoroethyl)piperidin-4-yl)methanamine (CAS 1182871-33-5)
- N-(2,2-difluoroethyl)-N-methylpiperidin-4-amine (CAS 1183504-76-8)
- N-(2,2-difluoroethyl)-1-methylpiperidin-4-amine (CAS 1184221-15-5)
- 1-(2,2-difluoroethyl)-2-ethylpiperazine (CAS 1341879-51-3)
- N1-(2,2-difluoroethyl)cyclohexane-1,3-diamine (CAS 1550039-52-5)
- 1-(2,2-Difluoroethyl)dihydropyrimidine-2,4(1H,3H)-dione (CAS 1545647-51-5)
- 2-(1,1-Difluoroethyl)-1,4-difluorobenzene (CAS 1138445-05-2)
- 2-(1,1-Difluoroethyl)-1,3-difluorobenzene (CAS 1138445-06-3)
Recommended Standards
- 3,3＇-Thiodipropionic Acid (CAS 111-17-1)
- H-Gly-Cys-OH (CAS 57281-78-4)
- Nifuratel Impurity 21 (CAS CATO-C4X-127221)
- Glutathione EP Impurity A (CAS 19246-18-5)
- N-(3-hydroxyphenyl)-5-methylisoxazole-3-carboxamide (CAS 688051-07-2)
- 2-Chloro-N-((6-methoxypyridazin-3-yl)methyl)acetamide (CAS 1353984-82-3)
- 3-(tert-Butyl)-4-chloro-5-cyclopropoxypyridine (CAS 1243370-08-2)
- 6,8-Dibromo-2-methylquinazolin-4(3H)-one (CAS 82326-77-0)
- 2-Fluoro-3-hydroxy-4-methoxybenzaldehyde (CAS 79418-73-8)
- 6-Amino-1-ethyl-5-(methylamino)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 131598-65-7)
- 2,3-Difluoro-5-methylbenzoyl chloride (CAS 1804417-80-8)
- 6,7-Dimethoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile, 97% (CAS 214470-52-7)
- 5-Chloro-4-methylnicotinic acid (CAS 890092-41-8)
- Cyclopeptide-5 (CAS 197172-76-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com