2-Fluoro-4-(3-methoxyphenyl)benzoic acid CAS 1178418-69-3
| CAS No. | 1178418-69-3 |
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Fluoro-4-(3-methoxyphenyl)benzoic acid (CAS 1178418-69-3) is a high-purity analytical reference standard with the molecular formula C14H11FO3 and a molecular weight of 246.23 g/mol.
2-Fluoro-4-(3-methoxyphenyl)benzoic acid (C14H11FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 3'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 106291-25-2)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1178021-58-3)
- 2-Fluoro-5-(2-methoxyphenyl)benzoic acid (CAS 1178303-59-7)
- 4-Fluoro-3-(3-methoxyphenyl)benzoic acid (CAS 1181452-19-6)
- 4-Fluoro-3-(2-methoxyphenyl)benzoic acid (CAS 1181639-56-4)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1182754-74-0)
- 2-Fluoro-4-(4-methoxyphenyl)benzoic acid (CAS 1183759-96-7)
- 2-Fluoro-5-(4-methoxyphenyl)benzoic acid (CAS 1183866-69-4)
Recommended Standards
- 2-[(2-Fluorophenoxy)methyl]benzoic acid (CAS 1156944-71-6)
- 5-(Benzyloxy)-2-fluorobenzoic acid (CAS 1148146-72-8)
- 2-[(3-Fluorophenoxy)methyl]benzoic Acid (CAS 114312-47-9)
- 4-(Benzyloxy)-2-fluorobenzoic acid (CAS 114045-96-4)
- (2,6-Difluoro-3,5-dimethoxyphenyl)hydrazine hydrochloride (CAS 1841081-46-6)
- 2-(3-Methoxy-2-methylphenyl)acetonitrile (CAS 33797-35-2)
- (9H-fluoren-9-yl)methyl (S)-4-isobutyl-5-oxooxazolidine-3-carboxylate (CAS 864966-70-1)
- S-(1H-Purin-6-yl) (2-chloroethyl)carbamothioate (CAS 104789-46-0)
- Benzyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (CAS 77497-96-2)
- 2-Cyclopropylbenzenesulfonyl chloride (CAS 1772586-39-6)
- Linaclotide impurity 45 (CAS 1331835-31-4)
- 1-Isopropyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydro-benzoimidazol-2-one (CAS 1373872-21-9)
- 2,4-Difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1454690-50-6)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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