2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid CAS 1178420-52-4

Description

2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid (CAS 1178420-52-4) is a high-purity analytical reference standard with the molecular formula C10H5Cl2NO2S and a molecular weight of 274.12 g/mol.

The molecular framework of 2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid (C10H5Cl2NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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