2-Fluoro-5-(4-trifluoromethoxyphenyl)benzoic acid CAS 1178497-48-7
| CAS No. | 1178497-48-7 |
| Molecular Formula | C14H8F4O3 |
| Molecular Weight | 300.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Fluoro-5-(4-trifluoromethoxyphenyl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Fluoro-5-(4-trifluoromethoxyphenyl)benzoic acid (CAS 1178497-48-7), a certified reference material (molecular formula C14H8F4O3, MW 300.21 g/mol) for analytical method development and quality control.
Structurally, 2-Fluoro-5-(4-trifluoromethoxyphenyl)benzoic acid (C14H8F4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 300.21 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F4O3 |
| Molecular Weight | 300.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-4-(4-trifluoromethoxyphenyl)benzoic acid (CAS 1178720-03-0)
- 4-Fluoro-4'-(trifluoromethoxy)biphenyl-2-carboxylic acid (CAS 1183674-44-3)
- 2-Fluoro-4'-(trifluoromethoxy)biphenyl-3-carboxylic acid (CAS 1261449-75-5)
- 4-Fluoro-3'-(trifluoromethoxy)biphenyl-2-carboxylic acid (CAS 1261460-00-7)
- 5-Fluoro-3-(3-trifluoromethoxyphenyl)benzoic acid (CAS 1261460-04-1)
- 3-Fluoro-4-(3-trifluoromethoxyphenyl)benzoic acid (CAS 1261524-83-7)
- 2-Fluoro-3'-(trifluoromethoxy)biphenyl-3-carboxylic acid (CAS 1261558-22-8)
- 3-fluoro-4-[2-(trifluoromethoxy)phenyl]benzoic acid (CAS 1261591-90-5)
Recommended Standards
- n-((5-Bromothiophen-2-yl)methyl)cyclohex-3-ene-1-carboxamide (CAS 1090579-06-8)
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- Abemaciclib Impurity 50 (CAS CATO-C4X-293750)
- Netupitant Impurity 63 (CAS CATO-C4X-122363)
- N-(piperidin-4-yl)pyridin-3-amine dihydrochloride (CAS 1010827-02-7)
- 4-Ethoxy-N,N,N-trimethyl-2,4-dioxo-1-butanaminium Chloride (CAS 10485-23-1)
- 1-Amino-3-(4-fluorophenyl)propan-2-ol (CAS 1225964-80-6)
- (S)-3-Amino-3-(pyridin-2-yl)propanamide (CAS 1213394-16-1)
- 4-((Tert-butyldimethylsilyl)oxy)-4-oxobutanoic acid (CAS 885519-54-0)
- Tert-butyl 4-(5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1062118-80-2)
- (2R,5S)-2,5-Bis(fluoromethyl)piperazine (CAS 790625-04-6)
- 3-(Cinnamylthio)-5-(pyridin-3-yl)-4H-1,2,4-triazol-4-amine (CAS 675842-04-3)
- (S)-1,4-Diaminobicyclo[2.2.2]octan-2-ol hydrochloride (CAS 2144478-61-3)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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