1-(3-Fluorophenyl)-2-(isopropylthio)ethan-1-one CAS 1178645-35-6
| CAS No. | 1178645-35-6 |
| Molecular Formula | C11H13FOS |
| Molecular Weight | 212.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Fluorophenyl)-2-(isopropylthio)ethan-1-one (CAS 1178645-35-6) is a high-purity analytical reference standard with the molecular formula C11H13FOS and a molecular weight of 212.28 g/mol.
The molecular framework of 1-(3-Fluorophenyl)-2-(isopropylthio)ethan-1-one (C11H13FOS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-Fluorophenyl)-2-(isopropylthio)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13FOS |
| Molecular Weight | 212.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 5-((2-Fluorophenyl)thio)pentan-2-one (CAS 1153114-76-1)
- 1-(3-Fluorophenyl)-2-(propylthio)ethan-1-one (CAS 1157206-88-6)
- 1-(2-Fluorophenyl)-2-(propylthio)ethan-1-one (CAS 1157364-02-7)
- 1-(4-Fluorophenyl)-2-(propylthio)ethan-1-one (CAS 1157364-22-1)
- 1-(4-Fluorophenyl)-2-(isopropylthio)ethan-1-one (CAS 1178684-31-5)
- 1-((2-Fluorophenyl)thio)pentan-2-one (CAS 1247627-80-0)
- 1-((4-Fluorophenyl)thio)pentan-2-one (CAS 1250917-71-5)
- 4-((4-Fluorophenyl)thio)pentan-2-one (CAS 1340028-38-7)
Recommended Standards
- 3-(Ethylthio)-1-(4-fluorophenyl)propan-1-one (CAS 1157736-71-4)
- 1-(1,1-Difluoro-ethyl)-4-n-pentyl-benzene (CAS 1186195-23-2)
- 2-(Ethylthio)-1-(4-fluorophenyl)propan-1-one (CAS 1157361-86-8)
- 1-(Ethylthio)-3-(4-fluorophenyl)propan-2-one (CAS 1157221-95-8)
- 3-Chloropyrrole-2-carbaldehyde (CAS 56164-42-2)
- 2-(3-Methyl-1H-indol-2-yl)acetonitrile (CAS 54124-41-3)
- 2-Propenoic acid, 2-methyl-, polymer with 2,3-dibromopropyl 2-propenoate and methyl 2-methyl-2-propenoate (CAS 52664-82-1)
- Triisopropyl((8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)ethynyl)silane (CAS 2454490-92-5)
- 17a(H),21B(H)-30-Norhopane (CAS 53584-60-4)
- 4-(Difluoromethyl)-3-fluoro-5-methylpyridin-2-ol (CAS 1806964-27-1)
- 3-(5-Isopropyl-2-methylphenoxy)piperidinehydrochloride (CAS 1219982-14-5)
- 2-(2,3-dihydro-1H-indol-1-ylmethyl)aniline (CAS 1016760-89-6)
- [(4-chlorophenyl)methyl][2-(pyrrolidin-1-yl)ethyl]amine dihydrochloride (CAS 105479-11-6)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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