3',4-Difluoro-[1,1'-biphenyl]-3-carboxylic acid CAS 1178958-75-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1178958-75-2
Molecular FormulaC13H8F2O2
Molecular Weight234.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3',4-Difluoro-[1,1'-biphenyl]-3-carboxylic acid CAS 1178958-75-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3',4-Difluoro-[1,1'-biphenyl]-3-carboxylic acid.

3',4-Difluoro-[1,1'-biphenyl]-3-carboxylic acid (CAS 1178958-75-2) is a high-purity analytical reference standard with the molecular formula C13H8F2O2 and a molecular weight of 234.20 g/mol.

Based on its molecular formula C13H8F2O2, 3',4-Difluoro-[1,1'-biphenyl]-3-carboxylic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 234.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H8F2O2
Molecular Weight234.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing

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