3-((Tert-butyldimethylsilyl)oxy)-2,2-dimethylpropan-1-ol CAS 117932-70-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-((Tert-butyldimethylsilyl)oxy)-2,2-dimethylpropan-1-ol.

3-((Tert-butyldimethylsilyl)oxy)-2,2-dimethylpropan-1-ol (CAS 117932-70-4) is a high-purity analytical reference standard with the molecular formula C11H26O2Si and a molecular weight of 218.41 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, 3-((Tert-butyldimethylsilyl)oxy)-2,2-dimethylpropan-1-ol is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-((Tert-butyldimethylsilyl)oxy)-2,2-dimethylpropan-1-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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