1-(5-Fluoro-2-hydroxyphenyl)-2-(isopropylthio)ethan-1-one CAS 1179721-72-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1179721-72-2
Molecular FormulaC11H13FO2S
Molecular Weight228.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(5-Fluoro-2-hydroxyphenyl)-2-(isopropylthio)ethan-1-one CAS 1179721-72-2 chemical structure

Description

The occurrence of 1-(5-Fluoro-2-hydroxyphenyl)-2-(isopropylthio)ethan-1-one is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-(5-Fluoro-2-hydroxyphenyl)-2-(isopropylthio)ethan-1-one (CAS 1179721-72-2), a certified reference material (molecular formula C11H13FO2S, MW 228.28 g/mol) for analytical method development and quality control.

The molecular framework of 1-(5-Fluoro-2-hydroxyphenyl)-2-(isopropylthio)ethan-1-one (C11H13FO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H13FO2S
Molecular Weight228.28 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Sulfur Atoms1

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