4-Chloro-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)picolinamide CAS 1179731-43-1
| CAS No. | 1179731-43-1 |
| Molecular Formula | C11H13ClN2O3S |
| Molecular Weight | 288.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)picolinamide.
4-Chloro-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)picolinamide (CAS 1179731-43-1), molecular formula C11H13ClN2O3S and molecular weight 288.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)picolinamide (C11H13ClN2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)picolinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13ClN2O3S |
| Molecular Weight | 288.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- tert-Butyl (R)-(2-amino-2-(3-chloro-5-fluorophenyl)ethyl)carbamate (CAS 1270082-86-4)
- 2-(1-Azepanyl)-N-methylethanamine (CAS 118808-13-2)
- 3-Quinolinecarbonitrile, 1,4-dihydro-6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-oxo- (CAS 1369509-89-6)
- 3-Methylazetidine-3-carboxylic acid hydrochloride (CAS 1365411-50-2)
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- 3-Bromo-6,7-dihydrooxepino[3,4-b]pyridin-9(5H)-one (CAS 2387600-31-7)
- 2-Chloro-N-(3-iodo-phenyl)-acetamide (CAS 2564-01-4)
- 1-(Tert-butoxycarbonyl)-3-(3-fluorophenyl)piperidine-3-carboxylic acid (CAS 1203682-37-4)
- Oxazolo[5,4-d]pyrimidin-7-ol (CAS 27433-54-1)
- 2-Ethyl-5-((4-fluorobenzyl)thio)-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline (CAS 1221715-40-7)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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