2-(Trifluoromethyl)thiazole-4-carbohydrazide CAS 1180526-68-4
| CAS No. | 1180526-68-4 |
| Molecular Formula | C5H4F3N3OS |
| Molecular Weight | 211.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Trifluoromethyl)thiazole-4-carbohydrazide (C5H4F3N3OS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(Trifluoromethyl)thiazole-4-carbohydrazide (CAS 1180526-68-4) is a high-purity analytical reference standard with the molecular formula C5H4F3N3OS and a molecular weight of 211.16 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4F3N3OS |
| Molecular Weight | 211.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 10444-99-2)
- 2-[2-(trifluoromethyl)-1,3-thiazol-4-yl]acetic acid (CAS 1082267-60-4)
- 2-(4-(Trifluoromethyl)thiazol-2-yl)acetic acid (CAS 1153298-70-4)
- 2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid (CAS 117724-63-7)
- 4-Methyl-2-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid (CAS 126889-06-3)
- Methyl 2-(trifluoromethyl)thiazole-4-carboxylate (CAS 1286734-79-9)
- Methyl 2-(trifluoromethyl)thiazole-5-carboxylate (CAS 1286734-94-8)
- Methyl 4-(trifluoromethyl)thiazole-5-carboxylate (CAS 1289104-53-5)
Recommended Standards
- (4-Bromobutyl)(isopropyl)sulfane (CAS 1179869-75-0)
- (3-Bromopropyl)(tert-butyl)sulfane (CAS 119549-23-4)
- 2-(2,2,2-Trifluoroethyl)-1,3-thiazole-4-carboxylic acid (CAS 1179338-11-4)
- 2,3,6-Trifluorobenzenesulfonamide (CAS 1204574-42-4)
- N,N-diethyl-3-(piperidin-4-yl)propanamide (CAS 1249844-79-8)
- N-(4-methylcycloheptyl)thietan-3-amine (CAS 1863034-30-3)
- 4-Amino-3-methyl-1-(m-tolyl)-1H-pyrazol-5-ol (CAS 802257-11-0)
- 7-Bromo-6-fluoroisoquinoline (CAS 923022-40-6)
- 1-(2-Hydroxyethyl)-3-nitro-1H-pyrazole-4-carboxamide (CAS 39205-83-9)
- (R)-2-(3,3-dimethylureido)-2-phenylacetic acid (CAS 1007879-93-7)
- 2-(Triethylsilyl)ethanol (CAS 2916-67-8)
- 4-Chloro-6-iodo-5-methylthieno[2,3-d]pyrimidine (CAS 1823372-30-0)
- 5-Propylisoxazol-3-amine (CAS 55809-37-5)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
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