2-((4'-(Tert-butyl)-[1,1'-biphenyl]-4-yl)oxy)acetic acid CAS 1181237-40-0
| CAS No. | 1181237-40-0 |
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((4'-(Tert-butyl)-[1,1'-biphenyl]-4-yl)oxy)acetic acid (CAS 1181237-40-0), molecular formula C18H20O3 and molecular weight 284.35 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, a hydroxyl group, an ether linkage, 2-((4'-(Tert-butyl)-[1,1'-biphenyl]-4-yl)oxy)acetic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Recommended Standards
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