2-amino-N-(prop-2-yn-1-yl)benzamide hydrochloride CAS 1181457-73-7
| CAS No. | 1181457-73-7 |
| Molecular Formula | C10H10N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-amino-N-(prop-2-yn-1-yl)benzamide hydrochloride (C10H10N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-amino-N-(prop-2-yn-1-yl)benzamide hydrochloride (CAS 1181457-73-7), molecular formula C10H10N2OHCl and molecular weight 210.66 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O HCl |
| Molecular Weight | 210.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- 6-Amino-7-hydroxy-2,3-dihydro-1H-inden-1-one hydrobromide (CAS 1000333-87-8)
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Recommended Standards
- 4-(Aminomethyl)-N-methylcyclohexane-1-carboxamide (CAS 1291486-36-6)
- 5-(3-Chloro-4-(methylsulfonyl)phenyl)-4-methylthiazol-2-amine (CAS 847789-30-4)
- 4-(4-Aminobutyl)pyridin-2-amine dihydrochloride (CAS 2138249-46-2)
- 5-((Methylamino)methyl)pyridin-2(1H)-one dihydrobromide (CAS 1949815-78-4)
- Capivasertib Impurity 48 (CAS CATO-C4X-331248)
- Mianserin Impurity 13 (CAS 91247-76-6)
- methyl 2-(oxolan-3-yl)ethanecarboximidate hydrochloride (CAS 1803584-59-9)
- 4-(Thiophen-2-yl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 933742-98-4)
- (4-Chloro-3-(morpholinomethyl)phenyl)boronic acid (CAS 1704073-83-5)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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