6-(4-Fluorophenyl)-2-(methylthio)pyrimidine-4-carboxylic acid CAS 1181727-83-2
| CAS No. | 1181727-83-2 |
| Molecular Formula | C12H9FN2O2S |
| Molecular Weight | 264.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-(4-Fluorophenyl)-2-(methylthio)pyrimidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
6-(4-Fluorophenyl)-2-(methylthio)pyrimidine-4-carboxylic acid (CAS 1181727-83-2) is a high-purity analytical reference standard with the molecular formula C12H9FN2O2S and a molecular weight of 264.28 g/mol.
The molecular framework of 6-(4-Fluorophenyl)-2-(methylthio)pyrimidine-4-carboxylic acid (C12H9FN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9FN2O2S |
| Molecular Weight | 264.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Diethyl 6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-dicarboxylate (CAS 117663-60-2)
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- 1172828-81-7 3-Isobutyl-6-methyl-4-oxo-3,4-dihydrofuro[2,3-d]pyrimidine-5-carbohydrazide MFCD14281967 (CAS 1172828-81-7)
- 6,9-Dioxa-3,12-diazatetradecane-1,14-dioic acid (CAS 117174-58-0)
- Ethyl 6-((tert-butoxycarbonyl)amino)picolinate (CAS 203321-86-2)
- 3-{4-methyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid (CAS 1235439-50-5)
- (3,3-Dimethylcyclopentyl)methanamine hydrochloride (CAS 1379304-45-6)
- 2-Amino-N-((6-chloropyridin-3-yl)methyl)acetamide (CAS 864273-38-1)
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- Methyl (2R)-2-hydroxy-2-(4-methoxyphenyl)acetate (CAS 32174-38-2)
- (3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenyl)boronic acid (CAS 1217501-31-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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