1-Bromo-2-(chloromethyl)-3-fluorobenzene CAS 1182357-16-9
| CAS No. | 1182357-16-9 |
| Molecular Formula | C7H5BrClF |
| Molecular Weight | 223.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Bromo-2-(chloromethyl)-3-fluorobenzene (CAS 1182357-16-9), a certified reference material (molecular formula C7H5BrClF, MW 223.47 g/mol) for analytical method development and quality control.
1-Bromo-2-(chloromethyl)-3-fluorobenzene (C7H5BrClF) contains fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-Bromo-2-(chloromethyl)-3-fluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrClF |
| Molecular Weight | 223.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 3-Bromo-4-chloro-5-fluorotoluene (CAS 1000576-14-6)
- 1-Bromo-2-chloro-5-fluoro-3-methylbenzene (CAS 1000576-68-0)
- 4-Bromo-2-(chloromethyl)-1-fluorobenzene (CAS 1020992-68-0)
- 2-Bromo-5-chloro-4-fluorotoluene (CAS 1067882-53-4)
- 1-Bromo-5-chloro-3-fluoro-2-methylbenzene (CAS 1082040-50-3)
- 1-Bromo-3-(chloromethyl)-5-fluorobenzene (CAS 1094651-50-9)
- 5-Bromo-3-chloro-2-fluorotoluene (CAS 1160574-49-1)
- 1-Bromo-4-(chloromethyl)-2-fluorobenzene (CAS 1214322-98-1)
Recommended Standards
- 2-Bromo-1-(chloromethyl)-3-fluorobenzene (CAS 1214382-68-9)
- 2-Bromo-5-chloro-1-fluoro-3-methylbenzene (CAS 1242339-10-1)
- 2-Bromo-3-chloro-5-fluorotoluene (CAS 1242339-16-7)
- 2-Bromo-4-chloro-5-fluorotoluene (CAS 1242339-82-7)
- Propan-2-yl 6-amino-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl}sulfanyl)methyl]-4-(3,5-dimethoxyphenyl)-4H-pyran-3-carboxylate (CAS 445384-31-6)
- 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-hexadecafluoro-1,8-diiodooctane 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-hexadecakis(fluoranyl)-1,8-bis(iodanyl)octane 335-70-6 A821850 (CAS 335-70-6)
- 3-(3-Fluorophenyl)prop-2-ynoic acid (CAS 705-83-9)
- Bradykinin (2-9) (CAS 16875-11-9)
- 3-Chloro-N-((3-chloro-5-fluorophenyl)carbamothioyl)benzamide (CAS 1796641-12-7)
- (2S,3R,4S,5S,6R)-2-(3,5-Dimethoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 90-71-1)
- 1-(2-Allylphenoxy)-3-(piperidin-1-yl)propan-2-ol (CAS 391219-51-5)
- (2E,4E)-2,4-Decadienoic Acid Methyl Ester (CAS 7328-33-8)
- Quinolin-8-yl trifluoromethanesulfonate (CAS 108530-08-1)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com