Loxoprofen Impurity 75 CAS 1182733-62-5
| CAS No. | 1182733-62-5 |
| Molecular Formula | C17H16F3N3OS |
| Molecular Weight | 367.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Loxoprofen Impurity 75 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Loxoprofen Impurity 75 (CAS 1182733-62-5, C17H16F3N3OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Loxoprofen Impurity 75 (C17H16F3N3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H16F3N3OS |
| Molecular Weight | 367.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Loxoprofen Standards
- Loxoprofen Impurity 140 (CAS CATO-C4X-1488140)
- Loxoprofen Impurity 113 (CAS CATO-C4X-1488113)
- Loxoprofen impurity 107 (CAS CATO-C4X-1488107)
- Loxoprofen impurity 135 (CAS CATO-C4X-1488135)
- Loxoprofen Impurity 76 (CAS CATO-C4X-148876)
- Loxoprofen Impurity 8 (CAS CATO-C4X-14888)
- Loxoprofen impurity 134 (CAS CATO-C4X-1488134)
- Loxoprofen Impurity 162 (CAS CATO-C4X-1488162)
Recommended Standards
- Lansoprazole impurity 65 (CAS CATO-C4X-111365)
- Retrorsine N-Oxide (CAS 15503-86-3)
- JACOBINE N‐OXIDE (CAS 38710-25-7)
- 9-(3-Hydroxypropyl)-3-(4-methoxyphenyl)-9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin-4-one (CAS 1010910-41-4)
- Lifitegrast Impurity 172 (CAS CATO-C4X-2409172)
- Methoxyphenamine Impurity 72 (CAS 71828-08-5)
- Cetirizine Impurity 22 (CAS 13391-38-3)
- 2-(4-Methyl-piperazin-1-yl)-ethylaminecarbonate (CAS 1185064-26-9)
- 2,7-Dimethyl-5-nitro-1,3-benzoxazole (CAS 1441051-52-0)
- tert-Butyl (4-(thiophen-3-yl)phenyl)carbamate (CAS 886505-43-7)
- cis-2-(4-Thioethylbenzoyl)cyclohexane-1-carboxylic acid (CAS 933674-61-4)
- 1-(3-amino-1-methyl-pyrazol-4-yl)ethanone (CAS 856860-18-9)
- 1-(Methyl-D3)-4-nitro-3-propyl-1H-pyrazole-5-carboxylic Acid (CAS 526203-29-2)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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