3,5-Difluoro-4-(4-methylpiperazin-1-yl)aniline CAS 1182736-56-6
| CAS No. | 1182736-56-6 |
| Molecular Formula | C11H15F2N3 |
| Molecular Weight | 227.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3,5-Difluoro-4-(4-methylpiperazin-1-yl)aniline (CAS 1182736-56-6), molecular formula C11H15F2N3 and molecular weight 227.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3,5-Difluoro-4-(4-methylpiperazin-1-yl)aniline (C11H15F2N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 227.25 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H15F2N3 |
| Molecular Weight | 227.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoro Standards
- 3-(3,4-Difluoro-5-methoxyphenyl)piperidine (CAS 1260885-33-3)
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- 4-Benzyl-6,6-difluoro-1,4-oxazepane (CAS 1934575-12-8)
- 7,7-difluoro-2-methylsulfanyl-5,6-dihydrocyclopenta[d]pyrimidine-4-carbonitrile (CAS 2843613-98-7)
- (S)-4,5-difluoro-2-(pyrrolidin-2-yl)benzoic acid (CAS 1213181-39-5)
- 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclobutanamine (CAS 1314696-88-2)
- 2-(3,3-Difluoro-2-oxoindolin-1-yl)acetic acid (CAS 1239462-73-7)
- 6,7-Difluoro-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 1269528-60-0)
Recommended Standards
- 3-(3,4-Difluorophenyl)-N-isopropylpropanamide (CAS 1181504-77-7)
- N-(3,5-difluorobenzyl)-1-(tetrahydrofuran-2-yl)methanamine (CAS 1183441-09-9)
- N-(3-(2,2-difluoroethoxy)benzyl)cyclopropanamine (CAS 1179136-66-3)
- N-(2-(2,2-difluoroethoxy)benzyl)cyclopropanamine (CAS 1184769-72-9)
- Ethyl 4-aminobenzofuran-2-carboxylate (CAS 1092351-93-3)
- Methyl 3-[4-fluoro-3-(trifluoromethyl)phenyl]benzoate (CAS 1820607-27-9)
- (1R,2R)-1,2-Bis(4-chlorophenyl)-N1,N2-dimethylethane-1,2-diamine (CAS 2444430-59-3)
- (5-Chloro-2-fluorophenyl)(phenyl)methanamine (CAS 1016530-22-5)
- (R)-3-(3-Fluorophenyl)piperazin-2-one (CAS 1228568-49-7)
- 2-[1-(aminomethyl)cyclopentyl]ethan-1-ol (CAS 1228748-75-1)
- H-Leu-His-OH (CAS 38062-72-5)
- Cenobamate Impurity 42 (CAS CATO-C4X-241642)
- Methyl 2-(4-methylcyclohexyl)acetate (CAS 344307-37-5)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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