3-(2-Chlorophenyl)cyclobutanol CAS 1182960-42-4
| CAS No. | 1182960-42-4 |
| Molecular Formula | C10H11ClO |
| Molecular Weight | 182.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 3-(2-Chlorophenyl)cyclobutanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3-(2-Chlorophenyl)cyclobutanol (CAS 1182960-42-4) is a high-purity analytical reference standard with the molecular formula C10H11ClO and a molecular weight of 182.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chlorophenyl)cyclobutanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO |
| Molecular Weight | 182.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 1-(2-Chlorophenyl)butan-2-one (CAS 103040-37-5)
- 3-(3-Chlorophenyl)cyclobutanol (CAS 1178487-43-8)
- 1-(3-Chlorophenyl)butan-2-one (CAS 1181404-78-3)
- 3-(4-Chlorophenyl)cyclobutan-1-ol (CAS 1184692-46-3)
- 2-(3-Chlorophenyl)-2-methylpropanal (CAS 1225521-01-6)
- (3-Chlorophenyl)(cyclopropyl)methanol (CAS 1225850-49-6)
- (2-(4-Chlorophenyl)cyclopropyl)methanol (CAS 1278662-50-2)
- 2-(2-Chlorophenyl)cyclobutan-1-ol (CAS 1315368-25-2)
Recommended Standards
- 4-Chloro-2-cyclopentylpyrimidine (CAS 1183726-54-6)
- 4-Chloro-2-cyclopropyl-5,6-dimethylpyrimidine (CAS 1184616-07-6)
- 8-Chloro-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 1175300-85-2)
- 2-Chloro-6-(pyrrolidin-1-yl)pyridine (CAS 117362-51-3)
- 2-{3-[(dimethylamino)methyl]phenyl}ethan-1-amine dihydrochloride (CAS 1305712-60-0)
- 5-Methyl-2-oxoimidazolidine-1-carboxamide (CAS 125577-53-9)
- 5-Bromo-2-(difluoromethyl)benzonitrile (CAS 1128269-99-7)
- Methyl 4-Amino-3-(cyclopropylamino)benzoate (CAS 1426958-47-5)
- Sofosbuvir Impurity 103 (CAS CATO-C4X-1052103)
- 3-(3-(4-Chloro-3-methyl-1h-pyrazol-1-yl)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one (CAS 1005563-76-7)
- 3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid (CAS 2950-82-5)
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole (CAS 1164458-36-9)
- 6-(3,4-Dimethylphenyl)-3-(piperidin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706432-95-2)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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