1-(2,2-Difluoroethyl)-1h-indazol-6-amine CAS 1183041-97-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1183041-97-5
Molecular FormulaC9H9F2N3
Molecular Weight197.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,2-Difluoroethyl)-1h-indazol-6-amine CAS 1183041-97-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 197.18 g/mol gives 1-(2,2-Difluoroethyl)-1h-indazol-6-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 1-(2,2-Difluoroethyl)-1h-indazol-6-amine (CAS 1183041-97-5), a certified reference material (molecular formula C9H9F2N3, MW 197.18 g/mol) for analytical method development and quality control.

The molecular framework of 1-(2,2-Difluoroethyl)-1h-indazol-6-amine (C9H9F2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2,2-Difluoroethyl)-1h-indazol-6-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H9F2N3
Molecular Weight197.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms3

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