Ziprasidone Impurity 10 CAS 118305-72-9

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.118305-72-9
Molecular FormulaC21H22N4OS
Molecular Weight378.49 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ziprasidone Impurity 10 CAS 118305-72-9 chemical structure

Description

CATO supplies Ziprasidone Impurity 10 (CAS 118305-72-9), a pharmacopoeial impurity reference standard (molecular formula C21H22N4OS, MW 378.49 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ziprasidone Impurity 10 (C21H22N4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H22N4OS
Molecular Weight378.49 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms4
Sulfur Atoms1

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