Methyl 2-methyl-2-(p-tolylamino)propanoate CAS 1183683-27-3
| CAS No. | 1183683-27-3 |
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 2-methyl-2-(p-tolylamino)propanoate (C12H17NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Methyl 2-methyl-2-(p-tolylamino)propanoate (CAS 1183683-27-3) is a high-purity analytical reference standard with the molecular formula C12H17NO2 and a molecular weight of 207.27 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Amino-N-isopropyl-N-(pyridin-3-ylmethyl)acetamide (CAS 1183419-10-4)
- (2-Methyl-benzyl)-piperidin-3-ylmethyl-amine hydrochloride (CAS 1185310-52-4)
- 5,6-Diethoxyindoline (CAS 1182792-37-5)
- 1-((6-Methoxypyridin-3-yl)methyl)piperazine (CAS 1185539-20-1)
- 2-Chloro-3-(2-methoxy-5-nitrophenoxymethyl)quinoline (CAS 1803599-75-8)
- 2,5-Bis((4-butoxybenzoyl)oxy)benzoic acid (CAS 205689-93-6)
- 1-(3-Chlorophenyl)-3-(1-(4-fluorobenzyl)-1H-pyrazol-3-yl)urea (CAS 1006199-61-6)
- EPZ005687 (CAS 1396772-26-1)
- 2-(3-Fluorophenoxy)-5-methylaniline (CAS 946728-41-2)
- 2-[(2-Fluorophenyl)amino]nicotinic acid (CAS 57978-54-8)
- 1-[(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)- 1H-Indazol-6-amine (CAS 315203-39-5)
- 1-(2-(Furan-3-yl)ethyl)-3-(4-methoxyphenyl)urea (CAS 1428371-20-3)
- 1-(2,6-difluorobenzyl)pyridinium bromide (CAS 646497-96-3)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com