4-(2,2-Difluoroethoxy)piperidine CAS 1183898-34-1
| CAS No. | 1183898-34-1 |
| Molecular Formula | C7H13F2NO |
| Molecular Weight | 165.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2,2-Difluoroethoxy)piperidine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2,2-Difluoroethoxy)piperidine (CAS 1183898-34-1) is a high-purity analytical reference standard with the molecular formula C7H13F2NO and a molecular weight of 165.18 g/mol.
The molecular framework of 4-(2,2-Difluoroethoxy)piperidine (C7H13F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H13F2NO |
| Molecular Weight | 165.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethoxy Standards
- 3-(2,2-Difluoroethoxy)piperidine (CAS 1247829-60-2)
- 2-(2,2-Difluoroethoxy)-2-methylpropanoic Acid (CAS 1447942-42-8)
- methyl 3-(2,2-difluoroethoxy)propanoate (CAS 1555117-94-6)
- 2-[2-(2,2-Difluoroethoxy)ethoxy]ethan-1-ol (CAS 1435806-96-4)
- 2-(2,2-Difluoroethoxy)pyridine (CAS 1849231-74-8)
- (2,2-Difluoroethoxy)benzene (CAS 1309602-18-3)
- 2-(2,2-Difluoroethoxy)aniline (CAS 937606-78-5)
- 3-(2,2-Difluoroethoxy)aniline (CAS 937603-10-6)
Recommended Standards
- n-(2,2-Difluoroethyl)oxan-4-amine (CAS 1183014-98-3)
- 1-(Aminomethyl)-3,3-difluorocyclohexan-1-ol (CAS 1227808-39-0)
- 2,2-Difluoro-N-((tetrahydrofuran-2-yl)methyl)ethan-1-amine (CAS 1182935-72-3)
- 1-(Aminomethyl)-4,4-difluorocyclohexan-1-ol (CAS 1227808-42-5)
- (E)-3-Methyl-4-phenylbut-3-en-2-one (CAS 42968-14-9)
- Bis(2-(bis(diethylamido)phosphino)phenyl) ether (CAS 391208-78-9)
- Methyl 2-amino-3-(4-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)phenyl)propanoate hydrochloride (CAS 724760-24-1)
- 4-Oxochromane-8-carbonitrile (CAS 911826-33-0)
- 2-Bromo-6-(trifluoromethyl)pyridine-4-methanol (CAS 1227499-07-1)
- (R)-1-(m-tolyl)butan-1-amine hydrochloride (CAS 698378-44-8)
- Gliquidone Impurity 4 (CAS 191988-38-2)
- 4,6-Dichloro-2-(4-chlorophenyl)pyrimidine (CAS 26870-72-4)
- 3-(2-Bromo-4-chlorophenoxy)pyrazine-2-carbonitrile (CAS 1253397-02-2)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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