(R)-methyl 3-chloro-2-methylpropanoate CAS 118417-75-7
| CAS No. | 118417-75-7 |
| Molecular Formula | C5H9ClO2 |
| Molecular Weight | 136.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (R)-methyl 3-chloro-2-methylpropanoate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(R)-methyl 3-chloro-2-methylpropanoate (CAS 118417-75-7) is a high-purity analytical reference standard with the molecular formula C5H9ClO2 and a molecular weight of 136.58 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, (R)-methyl 3-chloro-2-methylpropanoate is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 136.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-methyl 3-chloro-2-methylpropanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9ClO2 |
| Molecular Weight | 136.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
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