3-(5-Fluoropyridin-3-yl)prop-2-enoic acid CAS 118419-96-8
| CAS No. | 118419-96-8 |
| Molecular Formula | C8H5FNO2 |
| Molecular Weight | 166.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(5-Fluoropyridin-3-yl)prop-2-enoic acid (C8H5FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-(5-Fluoropyridin-3-yl)prop-2-enoic acid (CAS 118419-96-8) is a high-purity analytical reference standard with the molecular formula C8H5FNO2 and a molecular weight of 166.13 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(5-Fluoropyridin-3-yl)prop-2-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5FNO2 |
| Molecular Weight | 166.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoropyridin Standards
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- [1-(5-Fluoropyridin-2-yl)cyclopropyl]methanamine (CAS 1402233-01-5)
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- 3-(5-Fluoropyridin-2-yl)propiolic acid (CAS 1564793-56-1)
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- (E)-3-(2-Fluoropyridin-4-yl)acrylic acid (CAS 2493978-65-5)
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Recommended Standards
- 1-(difluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 1174305-81-7)
- 5-Acetylpyrazine-2-carboxylic acid (CAS 118543-96-7)
- 4,5-Dihydroxyisophthalaldehyde (CAS 116315-07-2)
- 1-(2-Nitropyridin-4-yl)ethan-1-one (CAS 1187669-56-2)
- 6-Bromo-3-methoxy-2-methylbenzonitrile (CAS 1420537-63-8)
- 4-bromo-2,2-dimethyl-2,3-dihydro-1H-inden-1-amine (CAS 1780310-91-9)
- N,N-Dimethylpiperazine-2-carboxamide dihydrochloride (CAS 1698027-03-0)
- 4-Amino-2-naphthoic acid (CAS 5773-98-8)
- (S)-2-Amino-N-[1-(3-chloro-phenyl)-ethyl]-N-isopropyl-3-methyl-butyramide (CAS 1354028-83-3)
- Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-,[1R-(exo,exo)]- (CAS 202280-03-3)
- 4-Amino-3-(3-(methoxymethyl)phenyl)butanoic acid (CAS 1497825-70-3)
- 2-Amino-7,7-dimethyl-5-oxo-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 153790-54-6)
- 2-Chloromethyl-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 1142400-61-0)
- Peptide 431 (CAS CATO-CPTD788431)
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