(1R,5S)-8-(3-chloro-5-fluorobenzyl)-8-azaspiro[bicyclo[3.2.1]Octane-3,2'-oxirane] CAS 1184917-32-5
| CAS No. | 1184917-32-5 |
| Molecular Formula | C15H17ClFNO |
| Molecular Weight | 281.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (1R,5S)-8-(3-chloro-5-fluorobenzyl)-8-azaspiro[bicyclo[3.2.1]Octane-3,2'-oxirane] under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(1R,5S)-8-(3-chloro-5-fluorobenzyl)-8-azaspiro[bicyclo[3.2.1]Octane-3,2'-oxirane] (CAS 1184917-32-5), molecular formula C15H17ClFNO and molecular weight 281.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (1R,5S)-8-(3-chloro-5-fluorobenzyl)-8-azaspiro[bicyclo[3.2.1]Octane-3,2'-oxirane] (C15H17ClFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 281.75 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H17ClFNO |
| Molecular Weight | 281.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ruxolitinib Impurity 63 (CAS CATO-C4X-205863)
- Dichlorobis(trimethylphosphine)nickel(II) (CAS 19232-05-4)
- Palbociclib Impurity 90 (CAS 2242625-36-9)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-fluoropyridine-6-carboxylic acid (CAS 1805523-30-1)
- n-((3-Methylpyridin-2-yl)methyl)-9h-purin-6-amine (CAS 1333786-16-5)
- 2-(4-Fluorophenyl)-7,8-dimethoxyquinolin-4-ol (CAS 1254973-33-5)
- 6-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine (CAS 1783932-03-5)
- 2,3-Dimethylpyrido[2,3-b]pyrazin-6(4H)-one (CAS 52996-62-0)
- 4-(5-(Benzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1-((4-methoxyphenyl)sulfonyl)piperidine (CAS 672950-67-3)
- 1-Chloro-3,6-diphenyl-9H-carbazole (CAS 2568667-14-9)
- 2-Chloro-3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridine (CAS 1447607-95-5)
- N-(4'-Cyano[1,1'-biphenyl]-4-yl)acetamide (CAS 215231-19-9)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com