3-{[(6-Bromo-2-naphthyl)oxy]methyl}piperidinehydrochloride CAS 1185133-11-2
| CAS No. | 1185133-11-2 |
| Molecular Formula | C16H18BrNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-{[(6-Bromo-2-naphthyl)oxy]methyl}piperidinehydrochloride.
CATO supplies 3-{[(6-Bromo-2-naphthyl)oxy]methyl}piperidinehydrochloride (CAS 1185133-11-2), a certified reference material (molecular formula C16H18BrNOHCl, MW 356.69 g/mol) for analytical method development and quality control.
The molecular framework of 3-{[(6-Bromo-2-naphthyl)oxy]methyl}piperidinehydrochloride (C16H18BrNOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18BrNO HCl |
| Molecular Weight | 356.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4,9-Bis(5-bromo-2-thienyl)-6,7-bis[4-[(2-ethylhexyl)oxy]phenyl][1,2,5]thiadiazolo[3,4-g]quinoxaline (CAS 1000000-25-8)
- 14-Bromo-1-tetradecyne (CAS 1000014-24-3)
- 8-Bromo-6-chloro-imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1000017-98-0)
- ethyl 3-bromo-5-chloroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1000018-03-0)
- 5-bromo-1-methyl-1H-indazol-3-amine (CAS 1000018-06-3)
- 5-Bromo-2-methyl-4-methylsulfonylphenylhydrazine (CAS 1000018-33-6)
- 1-[(5-Bromo-2-methyl-4-methylsulfonyl)phenyl]-piperidine-4-carboxamide (CAS 1000018-34-7)
- 1-[(5-Bromo-2-methyl-4-methylsulfonyl)phenyl]-piperazine (CAS 1000018-35-8)
Recommended Standards
- tert-Butyl (4-fluoro-2-methoxypyridin-3-yl)carbamate (CAS 175965-47-6)
- (2e)-3-[5-(3-bromophenyl)thiophen-2-yl]prop-2-enoic acid (CAS 1087784-22-2)
- Indene (CAS 95-13-6)
- 5,7-Dibromoindoline (CAS 221024-27-7)
- 5-Oxopyrrolidine-1,2-dicarboxylic acid (CAS 98109-83-2)
- Tegoprazan Impurity 132 (CAS CATO-C4X-2297132)
- 1-Ethyl-4-(prop-2-yn-1-yl)piperazine (CAS 220699-95-6)
- n-(4-Ethylcyclohexyl)-1-methyl-1h-pyrazol-4-amine (CAS 1153976-83-0)
- 3,3-Dimethyl-2-oxobutanenitrile (CAS 42867-40-3)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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