4-Iodo-3-methoxyaniline hydrochloride CAS 1185168-45-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1185168-45-9
Molecular FormulaC7H8INO
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Iodo-3-methoxyaniline hydrochloride CAS 1185168-45-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Iodo-3-methoxyaniline hydrochloride.

4-Iodo-3-methoxyaniline hydrochloride (CAS 1185168-45-9), molecular formula C7H8INOHCl and molecular weight 285.50 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Iodo-3-methoxyaniline hydrochloride (C7H8INOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Iodo-3-methoxyaniline hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H8INO HCl
Molecular Weight285.50 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1989
Halogen ContentCl/I-containing
Nitrogen Atoms1

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