1-(4-Bromophenyl)-6,7-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS 1185294-63-6
| CAS No. | 1185294-63-6 |
| Molecular Formula | C17H18BrN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(4-Bromophenyl)-6,7-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1185294-63-6), molecular formula C17H18BrNHCl and molecular weight 352.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Bromophenyl)-6,7-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (C17H18BrNHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-(4-Bromophenyl)-6,7-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18BrN HCl |
| Molecular Weight | 352.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenyl Standards
- 3-(4-Bromophenyl)indeno[1,2-c]pyrazol-4(1H)-one (CAS 100007-87-2)
- 3-(2-Bromophenyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole (CAS 1000339-25-2)
- 3-(2-Bromophenyl)-5-(2,4-dichlorophenyl)-1,2,4-oxadiazole (CAS 1000339-26-3)
- 3-(2-Bromophenyl)-5-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 1000339-27-4)
- 3-(2-Bromophenyl)-5-(2-chlorophenyl)-1,2,4-oxadiazole (CAS 1000339-28-5)
- 1-(4-Bromophenyl)-α,α-dimethyl-1H-1,2,3-triazole-4-methanol (CAS 1000339-34-3)
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- 2-(4-Bromophenyl)-2-(piperazin-1-yl)acetonitrile (CAS 1000406-20-1)
Recommended Standards
- 2-Chloro-5-[chloro(difluoro)methoxy]-1,3-difluoro-benzene (CAS 1417566-88-1)
- 4-(3-Piperidinylmethyl)phenol Hydrochloride (CAS 1170102-51-8)
- 1-Cyclopentyl-3,5-dinitro-1H-pyrazole (CAS 1281984-38-0)
- tert-Butyl 4-(4-oxocyclohexyl)piperazine-1-carboxylate (CAS 1262409-94-8)
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid (CAS 1380327-51-4)
- 1-(6-Cyclopropylpyrimidin-4-yl)piperidin-4-amine (CAS 1707735-23-6)
- 2-Amino-2-methylpropan-1-ol hydrobromide (CAS 23551-87-3)
- 2-(m-Tolyl)-2H-benzo[d][1,2,3]triazole (CAS 805316-08-9)
- 2-(3-Chlorophenyl)pyrrole (CAS 115464-89-6)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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